Role of Pseudomonas aeruginosa Peptidoglycan-Associated Outer Membrane Proteins in Vesicle Formation

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The role of Pseudomonas aeruginosa peptidoglycan-associated outer membrane proteins in vesicle formation

Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Texas, USA Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Texas, USA Cellular and Molecular Biology Program, Institute for Cellular and Molecular Biology, University of Texas at Austin, Texas, USA Dep...

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Role of Pseudomonas aeruginosa peptidoglycan-associated outer membrane proteins in vesicle formation.

Gram-negative bacteria produce outer membrane vesicles (OMVs) that package and deliver proteins, small molecules, and DNA to prokaryotic and eukaryotic cells. The molecular details of OMV biogenesis have not been fully elucidated, but peptidoglycan-associated outer membrane proteins that tether the outer membrane to the underlying peptidoglycan have been shown to be critical for OMV formation i...

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Pseudomonas aeruginosa outer membrane: peptidoglycan-associated proteins.

The Pseudomonas aeruginosa outer membrane was isolated with attached peptidoglycan and fractionated with Triton X-100, ethylenediaminetetraacetate, and lysozyme. The data suggest that major outer membrane proteins F, H2, and I are noncovalently associated with the peptidoglycan.

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Anchors Away : Determining the Role of Outer Membrane Proteins in Pseudomonas aeruginosa Vesicle Formation

ii DEDICATION First of all, I would like to thank Marvin for allowing me, back in January 2008, to work in his lab. This experience has enriched my undergraduate career by bringing textbook concepts to life. I am also grateful for the opportunity to have met and worked with such a great group of people. Thanks for this project go out to: Aimee Wessel, for her overall guidance and support (and c...

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Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa.

As an opportunistic Gram-negative pathogen, Pseudomonas aeruginosa must be able to adapt and survive changes and stressors in its environment during the course of infection. To aid survival in the hostile host environment, P. aeruginosa has evolved defense mechanisms, including the production of an exopolysaccharide capsule and the secretion of a myriad of degradative proteases and lipases. The...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2013

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.01253-12